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Targeting TRAIL Death Receptors in Triple-Negative Breast Cancers: Challenges and Strategies for Cancer Therapy

The tumor necrosis factor (TNF) superfamily member TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in cancer cells via death receptor (DR) activation with little toxicity to normal cells or tissues. The selectivity for activating apoptosis in cancer cells confers an ideal therapeutic...

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Detalles Bibliográficos
Autores principales: Kundu, Manjari, Greer, Yoshimi Endo, Dine, Jennifer L., Lipkowitz, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739296/
https://www.ncbi.nlm.nih.gov/pubmed/36496977
http://dx.doi.org/10.3390/cells11233717