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Targeting TRAIL Death Receptors in Triple-Negative Breast Cancers: Challenges and Strategies for Cancer Therapy
The tumor necrosis factor (TNF) superfamily member TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in cancer cells via death receptor (DR) activation with little toxicity to normal cells or tissues. The selectivity for activating apoptosis in cancer cells confers an ideal therapeutic...
Autores principales: | Kundu, Manjari, Greer, Yoshimi Endo, Dine, Jennifer L., Lipkowitz, Stanley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739296/ https://www.ncbi.nlm.nih.gov/pubmed/36496977 http://dx.doi.org/10.3390/cells11233717 |
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