Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity

Treating immunosuppressive tumors represents a major challenge in cancer therapies. Activation of STING signaling has shown remarkable potential to invigorate the immunologically “cold” tumor microenvironment (TME). However, we have shown that STING is silenced in many human cancers, including pancr...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Alameh, Mohamad-Gabriel, Yang, June F., Xu, Jonathan R., Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, You, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739380/
https://www.ncbi.nlm.nih.gov/pubmed/36498833
http://dx.doi.org/10.3390/ijms232314504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739380/
https://www.ncbi.nlm.nih.gov/pubmed/36498833
http://dx.doi.org/10.3390/ijms232314504

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