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The Role of Aldose Reductase in Beta-Amyloid-Induced Microglia Activation

The occurrence of Alzheimer’s disease has been associated with the accumulation of beta-amyloid (β-amyloid) plaques. These plaques activate microglia to secrete inflammatory molecules, which damage neurons in the brain. Thus, understanding the underlying mechanism of microglia activation can provide...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Kai, Liu, Chia-Chun, Wang, Shining, Cheng, Hui-Chun, Meadows, Chandler, Chang, Kun-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739496/
https://www.ncbi.nlm.nih.gov/pubmed/36499422
http://dx.doi.org/10.3390/ijms232315088