Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio

Changes in cortisol and other hormones during pregnancy may alter CYP3A enzymes activity, but data from sub-Saharan Africa are sparse. We investigated the effect of pregnancy and CYP3A5 genotypes on CYP3A enzymes activity using the plasma 4β-hydroxycholesterol (4β-OHC)/cholesterol (Chol) ratio, a kn...

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Detalles Bibliográficos
Autores principales: Mlugu, Eulambius M., Minzi, Omary M., Kamuhabwa, Appolinary A. R., Diczfalusy, Ulf, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739497/
https://www.ncbi.nlm.nih.gov/pubmed/36499500
http://dx.doi.org/10.3390/ijms232315168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739497/
https://www.ncbi.nlm.nih.gov/pubmed/36499500
http://dx.doi.org/10.3390/ijms232315168

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