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Investigating SH-SY5Y Neuroblastoma Cell Surfaceome as a Model for Neuronal-Targeted Novel Therapeutic Modalities

The SH-SY5Y neuroblastoma cells are a widely used in vitro model approximating neurons for testing the target engagement of therapeutics designed for neurodegenerative diseases and pain disorders. However, their potential as a model for receptor-mediated delivery and uptake of novel modalities, such...

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Detalles Bibliográficos
Autores principales: Gangras, Pooja, Gelfanova, Valentina, Williams, Graham D., Handelman, Samuel K., Smith, Ryan M., Debets, Marjoke F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739866/
https://www.ncbi.nlm.nih.gov/pubmed/36499391
http://dx.doi.org/10.3390/ijms232315062