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A Potent Antagonist of Smoothened in Hedgehog Signaling for Epilepsy

Epilepsy is one of the common encephalopathies caused by sudden abnormal discharges of neurons in the brain. About 30% of patients with epilepsy are insensitive and refractory to existing antiseizure medications. The sonic hedgehog signaling pathway is essential to the development and homeostasis of...

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Detalles Bibliográficos
Autores principales: Fan, Junwan, Zhao, Zichen, Liu, Ru, Li, Haowen, He, Wenyan, Wu, Jianping, Wang, Yongjun, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739937/
https://www.ncbi.nlm.nih.gov/pubmed/36498832
http://dx.doi.org/10.3390/ijms232314505