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A Potent Antagonist of Smoothened in Hedgehog Signaling for Epilepsy
Epilepsy is one of the common encephalopathies caused by sudden abnormal discharges of neurons in the brain. About 30% of patients with epilepsy are insensitive and refractory to existing antiseizure medications. The sonic hedgehog signaling pathway is essential to the development and homeostasis of...
Autores principales: | Fan, Junwan, Zhao, Zichen, Liu, Ru, Li, Haowen, He, Wenyan, Wu, Jianping, Wang, Yongjun, Chen, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739937/ https://www.ncbi.nlm.nih.gov/pubmed/36498832 http://dx.doi.org/10.3390/ijms232314505 |
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