Rh-Catalyzed Cascade C-H Activation/Annulation of N-Hydroxybenzamides and Propargylic Acetates for Modular Access to Isoquinolones

A sequential Rh(III)-catalyzed C-H activation/annulation of N-hydroxybenzamides with propargylic acetates leading to the formation of NH-free isoquinolones is described. This reaction proceeds through a sequential C-H activation/alkyne insertion/intramolecular annulation/N-O bond cleavage procedure,...

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Detalles Bibliográficos
Autores principales: Fang, Taibei, Zhang, Shiwen, Ye, Qingqing, Kong, Shuwen, Yang, Tingting, Tang, Kaijie, He, Xinwei, Shang, Yongjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740102/
https://www.ncbi.nlm.nih.gov/pubmed/36500644
http://dx.doi.org/10.3390/molecules27238553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740102/
https://www.ncbi.nlm.nih.gov/pubmed/36500644
http://dx.doi.org/10.3390/molecules27238553

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