PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage

DNA damage causes PARP1 activation in the nucleus to set up the machinery responsible for the DNA damage response. Here, we report that, in contrast to cytoplasmic PARPs, the synthesis of poly(ADP-ribose) by PARP1 opposes the formation of cytoplasmic mRNA-rich granules after arsenite exposure by red...

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Detalles Bibliográficos
Autores principales: Singatulina, Anastasia S., Sukhanova, Maria V., Desforges, Bénédicte, Joshi, Vandana, Pastré, David, Lavrik, Olga I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740212/
https://www.ncbi.nlm.nih.gov/pubmed/36497190
http://dx.doi.org/10.3390/cells11233932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740212/
https://www.ncbi.nlm.nih.gov/pubmed/36497190
http://dx.doi.org/10.3390/cells11233932

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