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Growth Hormone Improves Adipose Tissue Browning and Muscle Wasting in Mice with Chronic Kidney Disease-Associated Cachexia

Cachexia associated with chronic kidney disease (CKD) has been linked to GH resistance. In CKD, GH treatment enhances muscular performance. We investigated the impact of GH on cachexia brought on by CKD. CKD was induced by 5/6 nephrectomy in c57BL/6J mice. After receiving GH (10 mg/kg/day) or saline...

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Detalles Bibliográficos
Autores principales: Mak, Robert H., Gunta, Sujana, Oliveira, Eduardo A., Cheung, Wai W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740214/
https://www.ncbi.nlm.nih.gov/pubmed/36499637
http://dx.doi.org/10.3390/ijms232315310