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A Central Contribution of TG2 Activity to the Antiproliferative and Pro-Apoptotic Effects of Caffeic Acid in K562 Cells of Human Chronic Myeloid Leukemia

Caffeic acid (CA) has shown antitumor activity in numerous solid and blood cancers. We have recently reported that CA is active in reducing proliferation and triggering apoptosis in both Imatinib-sensitive and resistant Chronic Myeloid Leukemia (CML) cells. Tissue transglutaminase type 2 (TG2) enzym...

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Detalles Bibliográficos
Autores principales: Feriotto, Giordana, Tagliati, Federico, Brunello, Arianna, Beninati, Simone, Tabolacci, Claudio, Mischiati, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740221/
https://www.ncbi.nlm.nih.gov/pubmed/36499332
http://dx.doi.org/10.3390/ijms232315004