Inhibition of the MAPK/c-Jun-EGR1 Pathway Decreases Photoreceptor Cell Death in the rd1 Mouse Model for Inherited Retinal Degeneration

Retinitis pigmentosa (RP) is a group of inherited retinal dystrophies that typically results in photoreceptor cell death and vision loss. Here, we explored the effect of early growth response-1 (EGR1) expression on photoreceptor cell death in Pde6b(rd1) (rd1) mice and its mechanism of action. To thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Yujie, Xu, Wenrong, Li, Yan, Wei, Chunling, Hu, Yunzhang, Hu, Zhulin, Paquet-Durand, François, Jiao, Kangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740268/
https://www.ncbi.nlm.nih.gov/pubmed/36498926
http://dx.doi.org/10.3390/ijms232314600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740268/
https://www.ncbi.nlm.nih.gov/pubmed/36498926
http://dx.doi.org/10.3390/ijms232314600

Ejemplares similares