Complete Models of p53 Better Inform the Impact of Hotspot Mutations

Mutations in tumor suppressor genes often lead to cancerous phenotypes. Current treatments leverage signaling pathways that are often compromised by disease-derived deficiencies in tumor suppressors. P53 falls into this category as genetic mutations lead to physical changes in the protein that impac...

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Detalles Bibliográficos
Autores principales: Solares, Maria J., Kelly, Deborah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740296/
https://www.ncbi.nlm.nih.gov/pubmed/36499604
http://dx.doi.org/10.3390/ijms232315267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740296/
https://www.ncbi.nlm.nih.gov/pubmed/36499604
http://dx.doi.org/10.3390/ijms232315267

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