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Complete Models of p53 Better Inform the Impact of Hotspot Mutations
Mutations in tumor suppressor genes often lead to cancerous phenotypes. Current treatments leverage signaling pathways that are often compromised by disease-derived deficiencies in tumor suppressors. P53 falls into this category as genetic mutations lead to physical changes in the protein that impac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740296/ https://www.ncbi.nlm.nih.gov/pubmed/36499604 http://dx.doi.org/10.3390/ijms232315267 |