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Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice
With age, skeletal muscle undergoes a progressive decline in size and quality. Imbalanced mitochondrial turnover and the resultant dysfunction contribute to these phenotypic alterations. Motor neuron denervation (Den) is a contributor to the etiology of muscle atrophy associated with age. Further, a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740366/ https://www.ncbi.nlm.nih.gov/pubmed/36342767 http://dx.doi.org/10.18632/aging.204365 |