Insulitis in Human Type 1 Diabetic Pancreas: From Stem Cell Grafting to Islet Organoids for a Successful Cell-Based Therapy

Type 1 diabetes (T1D) is an autoimmune disease with immune cells’ islet infiltration (called “insulitis”), which leads to beta cell loss. Despite being the critical element of T1D occurrence and pathogenesis, insulitis is often present in a limited percentage of islets, also at diagnosis. Therefore,...

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Detalles Bibliográficos
Autores principales: La Noce, Marcella, Nicoletti, Giovanni Francesco, Papaccio, Gianpaolo, Del Vecchio, Vitale, Papaccio, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740394/
https://www.ncbi.nlm.nih.gov/pubmed/36497199
http://dx.doi.org/10.3390/cells11233941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740394/
https://www.ncbi.nlm.nih.gov/pubmed/36497199
http://dx.doi.org/10.3390/cells11233941

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