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Regulation of P-Glycoprotein in the Brain

Maintenance of the tightly regulated homeostatic environment of the brain is facilitated by the blood–brain barrier (BBB). P-glycoprotein (P-gp), an ATP-binding cassette transporter, is expressed on the luminal surface of the endothelial cells in the BBB, and actively exports a wide variety of subst...

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Detalles Bibliográficos
Autores principales: Chai, Amanda B., Callaghan, Richard, Gelissen, Ingrid C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740459/
https://www.ncbi.nlm.nih.gov/pubmed/36498995
http://dx.doi.org/10.3390/ijms232314667