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[(68)Ga]Ga-DATA(5m)-LM4, a PET Radiotracer in the Diagnosis of SST(2)R-Positive Tumors: Preclinical and First Clinical Results

Radiolabeled somatostatin subtype 2 receptor (SST2R)-antagonists have shown advantageous profiles for cancer theranostics compared with agonists. On the other hand, the newly introduced hybrid chelator (6-pentanoic acid)-6-(amino)methyl-1,4-diazepinetriacetate (DATA(5m)) rapidly binds Ga-68 (t(1/2):...

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Detalles Bibliográficos
Autores principales: Kanellopoulos, Panagiotis, Nock, Berthold A., Greifenstein, Lukas, Baum, Richard P., Roesch, Frank, Maina, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740503/
https://www.ncbi.nlm.nih.gov/pubmed/36498918
http://dx.doi.org/10.3390/ijms232314590