Quantitative Analysis of Isoniazid and Its Four Primary Metabolites in Plasma of Tuberculosis Patients Using LC-MS/MS

Isoniazid and its metabolites are potentially associated with hepatotoxicity and treatment outcomes in patients who receive antituberculosis (TB) therapy. To further understand the pharmacokinetic profiles of these molecules, a method based on LC-MS/MS was developed to determine the concentration of...

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Detalles Bibliográficos
Autores principales: Ky Anh, Nguyen, My Tung, Pham, Kim, Min Jung, Phuoc Long, Nguyen, Cho, Yong-Soon, Kim, Dong-Hyun, Shin, Jae-Gook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740544/
https://www.ncbi.nlm.nih.gov/pubmed/36500699
http://dx.doi.org/10.3390/molecules27238607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740544/
https://www.ncbi.nlm.nih.gov/pubmed/36500699
http://dx.doi.org/10.3390/molecules27238607

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