T-Cell Infiltration and Clonality May Identify Distinct Survival Groups in Colorectal Cancer: Development and Validation of a Prognostic Model Based on The Cancer Genome Atlas (TCGA) and Clinical Proteomic Tumor Analysis Consortium (CPTAC)

SIMPLE SUMMARY: Tumour-infiltrating T-cell abundance and clonality stratify the colorectal cancer risk of death. The very highly infiltrated cancers may constitute a distinct biological subset with an immunosuppressive microenvironment despite T-cell abundance and dismal prognosis. These tumours may...

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Detalles Bibliográficos
Autores principales: Campana, Luca G., Mansoor, Wasat, Hill, James, Macutkiewicz, Christian, Curran, Finlay, Donnelly, David, Hornung, Ben, Charleston, Peter, Bristow, Robert, Lord, Graham M., Valpione, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740634/
https://www.ncbi.nlm.nih.gov/pubmed/36497365
http://dx.doi.org/10.3390/cancers14235883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740634/
https://www.ncbi.nlm.nih.gov/pubmed/36497365
http://dx.doi.org/10.3390/cancers14235883

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