The Microtubule Destabilizer Eribulin Synergizes with STING Agonists to Promote Antitumor Efficacy in Triple-Negative Breast Cancer Models

SIMPLE SUMMARY: Microtubule-targeting agents are a class of chemotherapeutics used to treat triple-negative breast cancer (TNBC). These include drugs such as eribulin that depolymerize microtubules, as well as microtubule stabilizing taxanes such as paclitaxel. TNBC is a relatively immunogenic form...

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Detalles Bibliográficos
Autores principales: Takahashi-Ruiz, Leila, Fermaintt, Charles S., Wilkinson, Nancy J., Chan, Peter Y. W., Mooberry, Susan L., Risinger, April L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740651/
https://www.ncbi.nlm.nih.gov/pubmed/36497445
http://dx.doi.org/10.3390/cancers14235962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740651/
https://www.ncbi.nlm.nih.gov/pubmed/36497445
http://dx.doi.org/10.3390/cancers14235962

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