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Amyloid β-Peptide Causes the Permanent Activation of CaMKIIα through Its Oxidation
Alzheimer’s disease (AD) is characterised by the presence of extracellular amyloid plaques in the brain. They are composed of aggregated amyloid beta-peptide (Aβ) misfolded into beta-sheets which are the cause of the AD memory impairment and dementia. Memory depends on the hippocampal formation and...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740806/ https://www.ncbi.nlm.nih.gov/pubmed/36499491 http://dx.doi.org/10.3390/ijms232315169 |