Cargando…

Amyloid β-Peptide Causes the Permanent Activation of CaMKIIα through Its Oxidation

Alzheimer’s disease (AD) is characterised by the presence of extracellular amyloid plaques in the brain. They are composed of aggregated amyloid beta-peptide (Aβ) misfolded into beta-sheets which are the cause of the AD memory impairment and dementia. Memory depends on the hippocampal formation and...

Descripción completa

Detalles Bibliográficos
Autores principales: Picón-Pagès, Pol, Fanlo-Ucar, Hugo, Herrera-Fernández, Víctor, Ausellé-Bosch, Sira, Galera-López, Lorena, Gutiérrez, Daniela A., Ozaita, Andrés, Álvarez, Alejandra R., Oliva, Baldomero, Muñoz, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740806/
https://www.ncbi.nlm.nih.gov/pubmed/36499491
http://dx.doi.org/10.3390/ijms232315169