Pharmacological Inhibition of IKK to Tackle Latency and Hyperinflammation in Chronic HIV-1 Infection

HIV latent infection may be associated with disrupted viral RNA sensing, interferon (IFN) signaling, and/or IFN stimulating genes (ISG) activation. Here, we evaluated the use of compounds selectively targeting at the inhibitor of nuclear factor-κB (IκB) kinase (IKK) complex subunits and related kina...

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Detalles Bibliográficos
Autores principales: Ezeonwumelu, Ifeanyi Jude, Garcia-Vidal, Edurne, Riveira-Muñoz, Eva, Felip, Eudald, Gutiérrez-Chamorro, Lucía, Calba, Ignasi, Massanella, Marta, Sirera, Guillem, Clotet, Bonaventura, Ballana, Ester, Badia, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741028/
https://www.ncbi.nlm.nih.gov/pubmed/36499329
http://dx.doi.org/10.3390/ijms232315000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741028/
https://www.ncbi.nlm.nih.gov/pubmed/36499329
http://dx.doi.org/10.3390/ijms232315000

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