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Oxidative Stress and Extracellular Matrix Remodeling Are Signature Pathways of Extracellular Vesicles Released upon Morphine Exposure on Human Brain Microvascular Endothelial Cells

Morphine, a commonly used antinociceptive drug in hospitals, is known to cross the blood-brain barrier (BBB) by first passing through brain endothelial cells. Despite its pain-relieving effect, morphine also has detrimental effects, such as the potential induction of redox imbalance in the brain. Ho...

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Detalles Bibliográficos
Autores principales: Vujić, Tatjana, Schvartz, Domitille, Furlani, Izadora Liranço, Meister, Isabel, González-Ruiz, Víctor, Rudaz, Serge, Sanchez, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741159/
https://www.ncbi.nlm.nih.gov/pubmed/36497184
http://dx.doi.org/10.3390/cells11233926