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Canonical WNT Signaling Activated by WNT7B Contributes to L-HBs-Mediated Sorafenib Resistance in Hepatocellular Carcinoma by Inhibiting Mitophagy

SIMPLE SUMMARY: Hepatitis B virus (HBV) is the main cause of hepatocellular carcinoma (HCC) morbidity and mortality. Because of chemoresistance, sorafenib, the first-line systemic therapy for advanced HCC, has minimal advantages. According to recent research, HBV plays a role in sorafenib resistance...

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Detalles Bibliográficos
Autores principales: Liu, Li-Juan, Lv, Zhao, Xue, Xing, Xing, Zhong-Yuan, Zhu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741164/
https://www.ncbi.nlm.nih.gov/pubmed/36497264
http://dx.doi.org/10.3390/cancers14235781