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Adrenomedullin Mitigates Doxorubicin-Induced Nephrotoxicity in Rats: Role of Oxidative Stress, Inflammation, Apoptosis, and Pyroptosis

Doxorubicin (DOX) is an anticancer antibiotic which has various effects in human cancers. It is one of the commonly known causes of drug-induced nephrotoxicity, which results in acute renal injury. Adrenomedullin (ADM), a vasodilator peptide, is widely distributed in many tissues and has potent prot...

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Detalles Bibliográficos
Autores principales: Abd-Ellatif, Rania Nagi, Nasef, Nahla Anas, El-Horany, Hemat El-Sayed, Emam, Marwa Nagy, Younis, Reham Lotfy, El Gheit, Rehab E. Abo, Elseady, Walaa, Radwan, Doaa A., Hafez, Yasser Mostafa, Eissa, Ahmad, Aboalsoud, Alshimaa, Shalaby, Rania H., Atef, Marwa Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741179/
https://www.ncbi.nlm.nih.gov/pubmed/36498902
http://dx.doi.org/10.3390/ijms232314570