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Circulating Small Extracellular Vesicle-Derived miR-342-5p Ameliorates Beta-Amyloid Formation via Targeting Beta-site APP Cleaving Enzyme 1 in Alzheimer’s Disease

Alzheimer’s disease (AD) is a common neurodegenerative disorder with progressive cognitive impairment in the elderly. Beta-amyloid (Aβ) formation and its accumulation in the brain constitute one of the pathological hallmarks of AD. Until now, how to modulate Aβ formation in hippocampal neurons remai...

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Detalles Bibliográficos
Autores principales: Dong, Zhiwu, Gu, Hongjun, Guo, Qiang, Liu, Xianglu, Li, Feifei, Liu, Huiling, Sun, Li, Ma, Huimin, Zhao, Kewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741225/
https://www.ncbi.nlm.nih.gov/pubmed/36497090
http://dx.doi.org/10.3390/cells11233830