Different Intermolecular Interactions Drive Nonpathogenic Liquid–Liquid Phase Separation and Potentially Pathogenic Fibril Formation by TDP-43

The liquid–liquid phase separation (LLPS) of proteins has been found ubiquitously in eukaryotic cells, and is critical in the control of many biological processes by forming a temporary condensed phase with different bimolecular components. TDP-43 is recruited to stress granules in cells and is the...

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Detalles Bibliográficos
Autores principales: Zeng, Yu-Teng, Bi, Lu-Lu, Zhuo, Xiao-Feng, Yang, Ling-Yun, Sun, Bo, Lu, Jun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741235/
https://www.ncbi.nlm.nih.gov/pubmed/36499553
http://dx.doi.org/10.3390/ijms232315227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741235/
https://www.ncbi.nlm.nih.gov/pubmed/36499553
http://dx.doi.org/10.3390/ijms232315227

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