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Different Intermolecular Interactions Drive Nonpathogenic Liquid–Liquid Phase Separation and Potentially Pathogenic Fibril Formation by TDP-43

The liquid–liquid phase separation (LLPS) of proteins has been found ubiquitously in eukaryotic cells, and is critical in the control of many biological processes by forming a temporary condensed phase with different bimolecular components. TDP-43 is recruited to stress granules in cells and is the...

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Detalles Bibliográficos
Autores principales:	Zeng, Yu-Teng, Bi, Lu-Lu, Zhuo, Xiao-Feng, Yang, Ling-Yun, Sun, Bo, Lu, Jun-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741235/ https://www.ncbi.nlm.nih.gov/pubmed/36499553 http://dx.doi.org/10.3390/ijms232315227

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