Wild-Type Isocitrate Dehydrogenase-Dependent Oxidative Decarboxylation and Reductive Carboxylation in Cancer and Their Clinical Significance

SIMPLE SUMMARY: While isocitrate dehydrogenases have been known for decades, their mechanisms in tumors are gradually becoming clearer. The three isocitrate dehydrogenase isoforms in human cells differ in their subcellular localization, molecular structure, cofactor requirement, and catalytic mechan...

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Detalles Bibliográficos
Autores principales: He, Qiwei, Chen, Junxiong, Xie, Zijing, Chen, Zhenzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741289/
https://www.ncbi.nlm.nih.gov/pubmed/36497259
http://dx.doi.org/10.3390/cancers14235779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741289/
https://www.ncbi.nlm.nih.gov/pubmed/36497259
http://dx.doi.org/10.3390/cancers14235779

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