4-Methylumebelliferone Enhances Radiosensitizing Effects of Radioresistant Oral Squamous Cell Carcinoma Cells via Hyaluronan Synthase 3 Suppression

Radioresistant (RR) cells are poor prognostic factors for tumor recurrence and metastasis after radiotherapy. The hyaluronan (HA) synthesis inhibitor, 4-methylumbelliferone (4-MU), shows anti-tumor and anti-metastatic effects through suppressing HA synthase (HAS) expression in various cancer cells....

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Detalles Bibliográficos
Autores principales: Hasegawa, Kazuki, Saga, Ryo, Ohuchi, Kentaro, Kuwahara, Yoshikazu, Tomita, Kazuo, Okumura, Kazuhiko, Sato, Tomoaki, Fukumoto, Manabu, Tsuruga, Eichi, Hosokawa, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741296/
https://www.ncbi.nlm.nih.gov/pubmed/36497040
http://dx.doi.org/10.3390/cells11233780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741296/
https://www.ncbi.nlm.nih.gov/pubmed/36497040
http://dx.doi.org/10.3390/cells11233780

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