Identification of a Small Molecule Inhibitor of Hyaluronan Synthesis, DDIT, Targeting Breast Cancer Cells

SIMPLE SUMMARY: The most aggressive subtype of breast cancer, triple-negative breast cancer, is characterized by an excessive accumulation of hyaluronan in the cancer and its peritumoral stroma, which has been linked to poor prognosis of the patients. Inhibitors of hyaluronan synthesis would thus ha...

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Detalles Bibliográficos
Autores principales: Karalis, Theodoros, Shiau, Andrew K., Gahman, Timothy C., Skandalis, Spyros S., Heldin, Carl-Henrik, Heldin, Paraskevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741431/
https://www.ncbi.nlm.nih.gov/pubmed/36497283
http://dx.doi.org/10.3390/cancers14235800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741431/
https://www.ncbi.nlm.nih.gov/pubmed/36497283
http://dx.doi.org/10.3390/cancers14235800

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