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Microglia-Derived Olfactomedin-like 3 Is a Potent Angiogenic Factor in Primary Mouse Brain Endothelial Cells: A Novel Target for Glioblastoma

Neoangiogenesis, a hallmark feature of all malignancies, is robust in glioblastoma (GBM). Vascular endothelial growth factor (VEGF) has long been regarded as the primary pro-angiogenic molecule in GBM. However, anti-VEGF therapies have had little clinical efficacy, highlighting the need to explore V...

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Detalles Bibliográficos
Autores principales: Joseph, Laila M., Toedebusch, Ryan G., Debebe, Eshetu, Bastian, Aurelie H., Lucchesi, Christopher A., Syed-Quadri, Shafee, Wittenburg, Luke A., Chen, Xinbin, Meyers, Frederick J., Toedebusch, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741462/
https://www.ncbi.nlm.nih.gov/pubmed/36498941
http://dx.doi.org/10.3390/ijms232314613