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Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice

PURPOSE: To investigate the effect of canagliflozin (20 mg/kg) on hepatic steatosis and atherosclerosis, and further to explore its possible mechanism. METHODS: Blood glucose, blood lipid, oxidative stress response and inflammatory cytokines were examined by intraperitoneal glucose tolerance test an...

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Detalles Bibliográficos
Autores principales: Zuo, Qingjuan, Zhang, Guorui, He, Lili, Ma, Sai, Ma, Huijuan, Zhai, Jianlong, Wang, Zhongli, Zhang, Tingting, Wang, Yan, Guo, Yifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741490/
https://www.ncbi.nlm.nih.gov/pubmed/36510490
http://dx.doi.org/10.2147/DDDT.S388823