APOE ɛ4 allele and TOMM40‐APOC1 variants jointly contribute to survival to older ages

Age‐related diseases characteristic of post‐reproductive life, aging, and life span are the examples of polygenic non‐Mendelian traits with intricate genetic architectures. Polygenicity of these traits implies that multiple variants can impact their risks independently or jointly as combinations of...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Jain‐Washburn, Ethan, Philipp, Ian, He, Liang, Loika, Yury, Loiko, Elena, Bagley, Olivia, Ukraintseva, Svetlana, Yashin, Anatoliy, Arbeev, Konstantin, Stallard, Eric, Feitosa, Mary F., Schupf, Nicole, Christensen, Kaare, Culminskaya, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741507/
https://www.ncbi.nlm.nih.gov/pubmed/36330582
http://dx.doi.org/10.1111/acel.13730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741507/
https://www.ncbi.nlm.nih.gov/pubmed/36330582
http://dx.doi.org/10.1111/acel.13730

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