Myeloid cells promote interferon signaling-associated deterioration of the hematopoietic system

Innate and adaptive immune cells participate in the homeostatic regulation of hematopoietic stem cells (HSCs). Here, we interrogate the contribution of myeloid cells, the most abundant cell type in the mammalian bone marrow, in a clinically relevant mouse model of neutropenia. Long-term genetic depl...

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Detalles Bibliográficos
Autores principales: Feyen, Jacqueline, Ping, Zhen, Chen, Lanpeng, van Dijk, Claire, van Tienhoven, Tim V. D., van Strien, Paulina M. H., Hoogenboezem, Remco M., Wevers, Michiel J. W., Sanders, Mathijs A., Touw, Ivo P., Raaijmakers, Marc H. G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741615/
https://www.ncbi.nlm.nih.gov/pubmed/36496394
http://dx.doi.org/10.1038/s41467-022-35318-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741615/
https://www.ncbi.nlm.nih.gov/pubmed/36496394
http://dx.doi.org/10.1038/s41467-022-35318-x

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