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Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity

Knowledge of the transcriptional programs underpinning the functions of human kidney cell populations at homeostasis is limited. We present a single-cell perspective of healthy human kidney from 19 living donors, with equal contribution from males and females, profiling the transcriptome of 27677 ce...

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Detalles Bibliográficos
Autores principales: McEvoy, Caitriona M., Murphy, Julia M., Zhang, Lin, Clotet-Freixas, Sergi, Mathews, Jessica A., An, James, Karimzadeh, Mehran, Pouyabahar, Delaram, Su, Shenghui, Zaslaver, Olga, Röst, Hannes, Arambewela, Rangi, Liu, Lewis Y., Zhang, Sally, Lawson, Keith A., Finelli, Antonio, Wang, Bo, MacParland, Sonya A., Bader, Gary D., Konvalinka, Ana, Crome, Sarah Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741629/
https://www.ncbi.nlm.nih.gov/pubmed/36496458
http://dx.doi.org/10.1038/s41467-022-35297-z