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Transcriptome signatures preceding the induction of anti-stalk antibodies elicited after universal influenza vaccination

A phase 1 clinical trial to test the immunogenicity of a chimeric group 1 HA (cHA) universal influenza virus vaccine targeting the conserved stalk domain of the hemagglutinin of influenza viruses was carried out. Vaccination with adjuvanted-inactivated vaccines induced high anti-stalk antibody titer...

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Detalles Bibliográficos
Autores principales: Aydillo, Teresa, Gonzalez-Reiche, Ana S., Stadlbauer, Daniel, Amper, Mary Anne, Nair, Venugopalan D., Mariottini, Chiara, Sealfon, Stuart C., van Bakel, Harm, Palese, Peter, Krammer, Florian, García-Sastre, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741632/
https://www.ncbi.nlm.nih.gov/pubmed/36496417
http://dx.doi.org/10.1038/s41541-022-00583-w