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Chlamydia trachomatis suppresses host cell store-operated Ca(2+) entry and inhibits NFAT/calcineurin signaling

The obligate intracellular bacterium, Chlamydia trachomatis, replicates within a parasitophorous vacuole termed an inclusion. During development, host proteins critical for regulating intracellular calcium (Ca(2+)) homeostasis interact with the inclusion membrane. The inclusion membrane protein, Mrc...

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Detalles Bibliográficos
Autores principales: Chamberlain, Nicholas B., Dimond, Zoe, Hackstadt, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741641/
https://www.ncbi.nlm.nih.gov/pubmed/36496532
http://dx.doi.org/10.1038/s41598-022-25786-y