STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1

As diabetes results from the absolute or relative deficiency of insulin secretion from pancreatic β cells, possible methods to efficiently generate surrogate β cells have attracted a lot of efforts. To date, insulin-producing cells have been generated from various differentiated cell types in the pa...

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Detalles Bibliográficos
Autores principales: Wakabayashi, Yuka, Miyatsuka, Takeshi, Miura, Masaki, Himuro, Miwa, Taguchi, Tomomi, Iida, Hitoshi, Nishida, Yuya, Fujitani, Yoshio, Watada, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741642/
https://www.ncbi.nlm.nih.gov/pubmed/36496541
http://dx.doi.org/10.1038/s41598-022-25941-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741642/
https://www.ncbi.nlm.nih.gov/pubmed/36496541
http://dx.doi.org/10.1038/s41598-022-25941-5

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