Cargando…
STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1
As diabetes results from the absolute or relative deficiency of insulin secretion from pancreatic β cells, possible methods to efficiently generate surrogate β cells have attracted a lot of efforts. To date, insulin-producing cells have been generated from various differentiated cell types in the pa...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741642/ https://www.ncbi.nlm.nih.gov/pubmed/36496541 http://dx.doi.org/10.1038/s41598-022-25941-5 |