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Turning antibodies off and on again using a covalently tethered blocking peptide
In their natural form, antibodies are always in an “on-state” and are capable of binding to their targets. This leads to undesirable interactions in a wide range of therapeutic, analytical, and synthetic applications. Modulating binding kinetics of antibodies to turn them from an “off-state” to an “...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741643/ https://www.ncbi.nlm.nih.gov/pubmed/36496512 http://dx.doi.org/10.1038/s42003-022-04094-1 |