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CRL2(ZER1/ZYG11B) recognizes small N-terminal residues for degradation

N-degron pathway plays an important role in the protein quality control and maintenance of cellular protein homeostasis. ZER1 and ZYG11B, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2), recognize N-terminal (Nt) glycine degrons and participate in the Nt-myristoylation qualit...

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Detalles Bibliográficos
Autores principales: Li, Yao, Zhao, Yueling, Yan, Xiaojie, Ye, Chen, Weirich, Sara, Zhang, Bing, Wang, Xiaolu, Song, Lili, Jiang, Chenhao, Jeltsch, Albert, Dong, Cheng, Mi, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741652/
https://www.ncbi.nlm.nih.gov/pubmed/36496439
http://dx.doi.org/10.1038/s41467-022-35169-6