Cargando…

CRL2(ZER1/ZYG11B) recognizes small N-terminal residues for degradation

N-degron pathway plays an important role in the protein quality control and maintenance of cellular protein homeostasis. ZER1 and ZYG11B, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2), recognize N-terminal (Nt) glycine degrons and participate in the Nt-myristoylation qualit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yao, Zhao, Yueling, Yan, Xiaojie, Ye, Chen, Weirich, Sara, Zhang, Bing, Wang, Xiaolu, Song, Lili, Jiang, Chenhao, Jeltsch, Albert, Dong, Cheng, Mi, Wenyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741652/ https://www.ncbi.nlm.nih.gov/pubmed/36496439 http://dx.doi.org/10.1038/s41467-022-35169-6

Ejemplares similares

Slip slidin’ away of mitosis with CRL2(Zyg11)
por: Brandeis, Michael
Publicado: (2016)

The ubiquitin ligase CRL2(ZYG11) targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage
por: Balachandran, Riju S., et al.
Publicado: (2016)

Structural insights into ORF10 recognition by ZYG11B
por: Zhang, Bing, et al.
Publicado: (2022)

Site-Specific Phosphorylation of ZYG-1 Regulates ZYG-1 Stability and Centrosome Number
por: Medley, Jeffrey C., et al.
Publicado: (2023)

Site-specific phosphorylation of ZYG-1 regulates ZYG-1 stability and centrosome number
por: Medley, Jeffrey C., et al.
Publicado: (2023)

Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS
por: Tingaud‐Sequeira, Angèle, et al.
Publicado: (2020)

ZYG11A Is Expressed in Epithelial Ovarian Cancer and Correlates With Low Grade Disease
por: Achlaug, Laris, et al.
Publicado: (2021)

ZER1 Contributes to the Carcinogenic Activity of High-Risk HPV E7 Proteins
por: Nouel, Joangela, et al.
Publicado: (2022)

Development of A Tool for Assessing the Reputation of Zoos: The Zoo Ethical Reputation Survey (ZERS)
por: Spiriti, Maria Michela, et al.
Publicado: (2022)

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer
por: Achlaug, Laris, et al.
Publicado: (2019)

Silencing of circular RNA-ZYG11B exerts a neuroprotective effect against retinal neurodegeneration
por: Ma, Cong, et al.
Publicado: (2022)

Plk4/SAK/ZYG-1 in the regulation of centriole duplication
por: Pearson, Chad G, et al.
Publicado: (2010)

ZYG11A serves as an oncogene in non-small cell lung cancer and influences CCNE1 expression
por: Wang, Xin, et al.
Publicado: (2016)

ORF10–Cullin-2–ZYG11B complex is not required for SARS-CoV-2 infection
por: Mena, Elijah L., et al.
Publicado: (2021)

SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2(ZYG11B) activity
por: Wang, Liying, et al.
Publicado: (2022)

The CRL3(BTBD9) E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration
por: Li, Lihui, et al.
Publicado: (2020)

Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2(Prame) complex
por: Zhang, Wenjuan, et al.
Publicado: (2021)

PKC-Mediated ZYG1 Phosphorylation Induces Fusion of Myoblasts as well as of Dictyostelium Cells
por: Amagai, Aiko, et al.
Publicado: (2012)

Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication
por: Peel, Nina, et al.
Publicado: (2017)

Quantitative analyses for effects of neddylation on CRL2(VHL) substrate ubiquitination and degradation
por: Wang, Kankan, et al.
Publicado: (2021)

DNA hypomethylation-related overexpression of SFN, GORASP2 and ZYG11A is a novel prognostic biomarker for early stage lung adenocarcinoma
por: Husni, Ryan Edbert, et al.
Publicado: (2019)

PS-SiZer map to investigate significant features of body-weight profile changes in HIV infected patients in the IeDEA Collaboration
por: Harezlak, Jaroslaw, et al.
Publicado: (2020)

The p52-ZER6/G6PD axis alters aerobic glycolysis and promotes tumor progression by activating the pentose phosphate pathway
por: Tang, Yu, et al.
Publicado: (2023)

A ZYG-12–dynein interaction at the nuclear envelope defines cytoskeletal architecture in the C. elegans gonad
por: Zhou, Kang, et al.
Publicado: (2009)

CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination
por: Dewar, James M., et al.
Publicado: (2017)

Regulation of AMPK Activity by CRBN Is Independent of the Thalidomide-CRL4(CRBN) Protein Degradation Axis
por: Yang, Seung-Joo, et al.
Publicado: (2021)

CRL4B(DCAF11) E3 ligase targets p21 for degradation to control cell cycle progression in human osteosarcoma cells
por: Chen, Zhi, et al.
Publicado: (2017)

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex
por: Nightingale, Katie, et al.
Publicado: (2022)

Near zerO fluoroscopic exPosure during catheter ablAtion of supRavenTricular arrhYthmias: the NO-PARTY multicentre randomized trial
por: Casella, Michela, et al.
Publicado: (2016)

Zinc-finger protein p52-ZER6 accelerates colorectal cancer cell proliferation and tumour progression through promoting p53 ubiquitination
por: Huang, Can, et al.
Publicado: (2019)

LncRNA LINC01871 sponging miR-142-3p to modulate ZYG11B promotes the chemoresistance of colorectal cancer cells by inducing autophagy
por: Duan, Bensong, et al.
Publicado: (2023)

Structure of CRL2(Lrr1), the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates
por: Zhou, Haixia, et al.
Publicado: (2021)

CRL3(IBTK) Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation
por: Pisano, Antonio, et al.
Publicado: (2015)

CRL Ubiquitin Ligases and DNA Damage Response
por: Li, Ju-Mei, et al.
Publicado: (2012)

Binding interface between the Salmonella σ(S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl
por: Cavaliere, Paola, et al.
Publicado: (2015)

Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
por: Le‐Trilling, Vu Thuy Khanh, et al.
Publicado: (2023)

Antitoxin CrlA of CrlTA Toxin–Antitoxin System in a Clinical Isolate Pseudomonas aeruginosa Inhibits Lytic Phage Infection
por: Ni, Muyang, et al.
Publicado: (2022)

ZYG-9, A Caenorhabditis elegans Protein Required for Microtubule Organization and Function, Is a Component of Meiotic and Mitotic Spindle Poles
por: Matthews, Lisa R., et al.
Publicado: (1998)

ZYG-9(ch-TOG) promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis
por: Cavin-Meza, Gabriel, et al.
Publicado: (2022)

SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation
por: Jørgensen, Stine, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_7af6cp23ng5bqp3746jjse7uut