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EV-A71 induced IL-1β production in THP-1 macrophages is dependent on NLRP3, RIG-I, and TLR3

Enterovirus A71 (EV-A71) is an emerging enterovirus that can cause neurological complications. Enhanced serum IL-1β levels were observed in EV-A71 patients with severe neurological symptoms. However, the roles of sensors in enterovirus-induced IL-1β production are unclear. In this study, we identifi...

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Detalles Bibliográficos
Autores principales: Huang, Hsing-I, Chio, Chi-Chong, Lin, Jhao-Yin, Chou, Chia-Jung, Lin, Chia-Chen, Chen, Shih-Hsiang, Yu, Liang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741760/
https://www.ncbi.nlm.nih.gov/pubmed/36503883
http://dx.doi.org/10.1038/s41598-022-25458-x