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Biomimetic calcium carbonate nanoparticles delivered IL-12 mRNA for targeted glioblastoma sono-immunotherapy by ultrasound-induced necroptosis

Glioblastoma (GBM) is the most aggressive brain tumor, which owns the characteristics of high recurrence, low survival rate and poor prognosis because of the existence of blood brain barrier (BBB) and complicated brain tumor microenvironment. Currently, immunotherapy has attracted much attention on...

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Detalles Bibliográficos
Autores principales: Zhao, Pengxuan, Tian, Yu, Lu, Yongping, Zhang, Jun, Tao, Anyu, Xiang, Guangya, Liu, Yani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741778/
https://www.ncbi.nlm.nih.gov/pubmed/36496387
http://dx.doi.org/10.1186/s12951-022-01731-z