Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis

BACKGROUND: Hyaluronan receptor LYVE-1 is expressed by liver sinusoidal endothelial cells (LSEC), lymphatic endothelial cells and specialized macrophages. Besides binding to hyaluronan, LYVE-1 can mediate adhesion of leukocytes and cancer cells to endothelial cells. Here, we assessed the impact of L...

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Detalles Bibliográficos
Autores principales: Jauch, Anna Sophia, Wohlfeil, Sebastian A., Weller, Céline, Dietsch, Bianca, Häfele, Verena, Stojanovic, Ana, Kittel, Maximilian, Nolte, Hendrik, Cerwenka, Adelheid, Neumaier, Michael, Schledzewski, Kai, Sticht, Carsten, Reiners-Koch, Philipp-Sebastian, Goerdt, Sergij, Géraud, Cyrill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741792/
https://www.ncbi.nlm.nih.gov/pubmed/36496412
http://dx.doi.org/10.1186/s12935-022-02800-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741792/
https://www.ncbi.nlm.nih.gov/pubmed/36496412
http://dx.doi.org/10.1186/s12935-022-02800-x

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