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Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis

BACKGROUND: Hyaluronan receptor LYVE-1 is expressed by liver sinusoidal endothelial cells (LSEC), lymphatic endothelial cells and specialized macrophages. Besides binding to hyaluronan, LYVE-1 can mediate adhesion of leukocytes and cancer cells to endothelial cells. Here, we assessed the impact of L...

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Detalles Bibliográficos
Autores principales:	Jauch, Anna Sophia, Wohlfeil, Sebastian A., Weller, Céline, Dietsch, Bianca, Häfele, Verena, Stojanovic, Ana, Kittel, Maximilian, Nolte, Hendrik, Cerwenka, Adelheid, Neumaier, Michael, Schledzewski, Kai, Sticht, Carsten, Reiners-Koch, Philipp-Sebastian, Goerdt, Sergij, Géraud, Cyrill
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741792/ https://www.ncbi.nlm.nih.gov/pubmed/36496412 http://dx.doi.org/10.1186/s12935-022-02800-x

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