Simple IHC reveals complex MMR alternations than PCR assays: Validation by LCM and next‐generation sequencing

Evaluation of the status of mismatch repair (MMR) in tumors is crucial for determining the application of immune checkpoint inhibitors (ICIs). Conventional PCR (MSI‐PCR) is the gold standard for confirming the MMR status. However, it requires visual confirmation and presents difficulties in determin...

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Detalles Bibliográficos
Autores principales: Amemiya, Kenji, Hirotsu, Yosuke, Nagakubo, Yuki, Watanabe, Shunsuke, Amemiya, Saki, Mochizuki, Hitoshi, Oyama, Toshio, Kondo, Tetsuo, Omata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741978/
https://www.ncbi.nlm.nih.gov/pubmed/35596629
http://dx.doi.org/10.1002/cam4.4832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741978/
https://www.ncbi.nlm.nih.gov/pubmed/35596629
http://dx.doi.org/10.1002/cam4.4832

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